AFF3

Across TCGA patient cohorts, AFF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,398 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AFF3-associated proteins across cancer lineages are RO60, CDKN1B, and EIF4G1. Each is linked with AFF3 in more than 7 cancer types. Because this analysis shows association rather than direction, both AFF3-to-partner and partner-to-AFF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AFF3 versus RO60 in OV, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFF3→partner) and Y-score (partner→AFF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RO60 →	+0.265	+0.382	<.001	.001	3	8
OV	CDKN1B →	+0.447	+0.408	.005	.003	3	7
LSCC	EIF4G1 →	-0.310	-0.949	<.001	<.001	3	7
HNSC	ERO1A →	-0.635	-0.528	<.001	<.001	3	7
BRCA	HDGFL3 →	+0.746	+2.180	<.001	<.001	3	7
COAD	LAMB2 →	+0.664	+0.181	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,398 associations by consensus.

AFF3 vs RO60 — OV

Explore this scatter interactively →