AFF2

Across TCGA cell cohorts, AFF2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,056 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AFF2-associated genes across cancer lineages are GAPDH, ABCE1, and LIPE. Each is linked with AFF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both AFF2-to-partner and partner-to-AFF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AFF2 versus GAPDH in STOMACH, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AFF2→partner) and Y-score (partner→AFF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	GAPDH →	+1.060	+2.534	.003	<.001	3	5
STOMACH	ABCE1 →	+0.961	+1.629	.003	.007	2	6
BLOOD_Leukemia	LIPE →	+1.837	+1.672	<.001	.001	3	5
BLOOD_Leukemia	NCF1 →	-2.784	-2.115	<.001	<.001	3	4
OESOPHAGUS	C3 →	-2.263	-1.135	.001	.001	3	4
CNS	ILRUN →	-0.454	-1.090	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,056 associations by consensus.

AFF2 vs GAPDH — STOMACH

Explore this scatter interactively →