Across TCGA patient cohorts, AFAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,618 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AFAP1-associated proteins across cancer lineages are AFAP1_S668, AFAP1_S548, and AFAP1_S711. Each is linked with AFAP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both AFAP1-to-partner and partner-to-AFAP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AFAP1→partner) and Y-score (partner→AFAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AFAP1_S668 →	+0.831	+0.891	.001	<.001	3	9
OV	AFAP1_S548 →	+0.977	+0.743	<.001	<.001	3	8
LSCC	AFAP1_S711 →	+1.012	+0.760	<.001	<.001	3	8
OV	VCAN →	+1.352	+0.733	<.001	.001	3	7
OV	MLYCD →	-0.448	-0.680	<.001	.002	3	7
OV	TIMP2 →	+0.542	+0.583	.004	.009	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,618 associations by consensus.

Exploration

AFAP1 survival (RNA) · tumor vs normal (RNA) · all AFAP1 data types