AEBP2

Across TCGA cell cohorts, AEBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,591 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AEBP2-associated GO terms across cancer lineages are RNA destabilization, mRNA destabilization, and Positive regulation of mRNA metabolic process. Each is linked with AEBP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both AEBP2-to-partner and partner-to-AEBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA destabilization grouped by AEBP2-low versus AEBP2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AEBP2→partner) and Y-score (partner→AEBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	RNA destabilization →	+0.074	+0.858	<.001	<.001	3	13
URINARY_TRACT	mRNA destabilization →	+0.075	+0.796	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of mRNA metabolic process →	+0.067	+0.769	<.001	.002	3	13
BLOOD_Lymphoma	Positive regulation of mRNA catabolic process →	+0.061	+1.044	.001	.004	3	12
SOFT_TISSUE	mRNA export from nucleus →	+0.081	+0.644	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.077	+0.861	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,591 associations by consensus.

RNA destabilization by AEBP2 expression — URINARY_TRACT

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