AEBP2

Across TCGA cell cohorts, AEBP2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AEBP2-associated genes across cancer lineages are TCP11X2, OR2L5, and OPN1MW. Each is linked with AEBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AEBP2-to-partner and partner-to-AEBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCP11X2 grouped by AEBP2-low versus AEBP2-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AEBP2→partner) and Y-score (partner→AEBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TCP11X2 →	+0.123	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR2L5 →	+0.012	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	OPN1MW →	+0.147	+4.887	<.001	.009	3	1
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
LARGE_INTESTINE	PROP1 →	+0.032	+4.054	<.001	.004	3	1
CNS	SHISAL2B →	+0.985	+4.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

TCP11X2 by AEBP2 expression — URINARY_TRACT

Explore this box plot interactively →