AEBP1

Across TCGA pan-cancer cohorts, AEBP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated AEBP1 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher AEBP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated AEBP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LSCC, CCRCC, and COAD are the cancer types where AEBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.714	0.965	<.001	32	view →
CCRCC	DFS	Median	III,IV	0.399	0.932	.022	15	view →
COAD	DFS	Median	III,IV	0.829	1.000	.027	12	view →
HNSC	DFS	Median	II,III,IV	0.967	0.904	.034	6	view →
LUAD	OS	Median	III,IV	0.440	0.773	.012	5	view →
GBM	OS	Median	All	0.768	0.945	.027	5	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

AEBP1–LSCC (OS)

Open the LSCC breakdown →