ADTRP

Across TCGA cell cohorts, ADTRP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,540 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADTRP-associated GO terms across cancer lineages are Negative regulation of dendritic cell antigen processing and presentation, Regulation of calcium ion transport into cytosol, and Angiogenesis. Each is linked with ADTRP in more than 11 cancer types. Because this analysis shows association rather than direction, both ADTRP-to-partner and partner-to-ADTRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of dendritic cell antigen processing and presentation grouped by ADTRP-low versus ADTRP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADTRP→partner) and Y-score (partner→ADTRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of dendritic cell antigen processing and presentation →	+1.735	+0.852	<.001	<.001	3	12
SOFT_TISSUE	Regulation of calcium ion transport into cytosol →	+0.260	+1.186	<.001	<.001	3	10
BONE	Angiogenesis →	+0.107	+0.692	<.001	<.001	3	10
LIVER	Negative regulation of dendritic cell apoptotic process →	+2.096	+1.496	<.001	<.001	3	10
BONE	Regulation of smooth muscle cell-matrix adhesion →	+0.854	+1.065	.001	<.001	3	10
SOFT_TISSUE	Regulation of proteolysis →	+0.106	+1.175	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,540 associations by consensus.

Negative regulation of dendritic cell antigen processing and presentation by ADTRP expression — BONE

Explore this box plot interactively →