ADSS2

Across TCGA cell cohorts, ADSS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,934 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADSS2-associated GO terms across cancer lineages are Nuclear pore organization, Nuclear pore complex assembly, and Regulation of protein K48-linked deubiquitination. Each is linked with ADSS2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ADSS2-to-partner and partner-to-ADSS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by ADSS2-low versus ADSS2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADSS2→partner) and Y-score (partner→ADSS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear pore organization →	+0.127	+0.720	<.001	<.001	3	14
BLOOD_Myeloma	Nuclear pore complex assembly →	+0.115	+0.854	.001	<.001	3	12
PANCREAS	Regulation of protein K48-linked deubiquitination →	-0.050	-0.569	<.001	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.103	+0.792	<.001	<.001	3	10
LUNG_SCLC	'de novo' AMP biosynthetic process →	+0.167	+0.749	<.001	<.001	3	10
BLOOD_Leukemia	Vesicle tethering involved in exocytosis →	+0.072	+0.545	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,934 associations by consensus.

Nuclear pore organization by ADSS2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →