Across TCGA pan-cancer cohorts, ADSS1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ADSS1 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ADSS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ADSS1 expression acts as an unfavorable survival marker.

STAD, ACC, and SKCM are the cancer types where ADSS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	III,IV	0.184	0.641	.011	9	view →
ACC	OS	Median	All	0.188	0.633	.035	4	view →
SKCM	OS	Median	II,III,IV	0.500	0.744	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ADSS1 tumor-vs-normal RNA expression · all ADSS1 data types