ADSS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADSS1 mutation is significantly associated with the RNA expression of many other genes, with 1,189 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADSS1-associated genes across cancer lineages are USH2A-AS1, SS18L2P2, and SLC7A11. Each is linked with ADSS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADSS1-to-partner and partner-to-ADSS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADSS1→partner) and Y-score (partner→ADSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMUSH2A-AS1 →+0.088+3.978<.001<.00132
COADSS18L2P2 →+0.100+3.917<.001.00932
UCECSLC7A11 →+1.163+2.600<.001.00632
UCECFAM177A1 →+0.387+3.491.003.00232
UCECSLC25A4 →+0.560+2.831.001.00132
UCECSEC13 →+0.416+2.848.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,189 associations by consensus.

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