ADSL

Across TCGA pan-cancer cohorts, ADSL Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated ADSL data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ADSL Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ADSL expression acts as an unfavorable survival marker.

ACC, LUAD, and SARC are the cancer types where ADSL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.010	0.667	<.001	45	view →
LUAD	OS	Median	II,III,IV	0.090	0.677	<.001	16	view →
SARC	DFS	Median	All	0.054	0.613	<.001	15	view →
BLCA	OS	Median	IV	0.051	0.600	<.001	12	view →
LIHC	DFS	Median	All	0.038	0.553	<.001	12	view →
COAD	OS	Median	IV	0.056	0.649	<.001	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ADSL–ACC (DFS)

Open the ACC breakdown →