ADSL

Across TCGA patient cohorts, ADSL protein abundance is significantly associated with the RNA expression of many other genes, with 5,768 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADSL-associated genes across cancer lineages are SLC25A17, PHF5A, and TOMM22. Each is linked with ADSL in more than 6 cancer types. Because this analysis shows association rather than direction, both ADSL-to-partner and partner-to-ADSL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADSL versus SLC25A17 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADSL→partner) and Y-score (partner→ADSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC25A17 →	+0.516	+0.335	<.001	<.001	3	7
LSCC	PHF5A →	+0.693	+0.397	<.001	<.001	3	7
HNSC	TOMM22 →	+0.590	+0.227	.001	<.001	3	6
LSCC	EIF3D →	+0.636	+0.362	<.001	<.001	3	6
LSCC	XRCC6 →	+0.644	+0.343	<.001	<.001	3	6
COAD	RBX1 →	+0.605	+0.213	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,768 associations by consensus.

ADSL vs SLC25A17 — LSCC

Explore this scatter interactively →