ADSL

Across TCGA cell cohorts, ADSL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,855 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ADSL-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, DNA replication initiation, and Nucleolar large rRNA transcription by RNA polymerase I. Each is linked with ADSL in more than 17 cancer types. Because this analysis shows association rather than direction, both ADSL-to-partner and partner-to-ADSL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by ADSL-low versus ADSL-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADSL→partner) and Y-score (partner→ADSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	'de novo' IMP biosynthetic process →	+0.165	+0.949	.002	.001	3	18
PANCREAS	DNA replication initiation →	+0.173	+1.078	<.001	<.001	3	17
OESOPHAGUS	Nucleolar large rRNA transcription by RNA polymerase I →	+0.135	+0.843	<.001	.003	3	16
URINARY_TRACT	Transcription initiation at RNA polymerase I promoter →	+0.105	+1.047	.001	.001	3	16
BONE	Mitotic sister chromatid cohesion →	+0.140	+0.795	<.001	<.001	3	16
SOFT_TISSUE	DNA-templated DNA replication →	+0.127	+0.773	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,855 associations by consensus.

'de novo' IMP biosynthetic process by ADSL expression — OESOPHAGUS

Explore this box plot interactively →