ADRM1

Across TCGA pan-cancer cohorts, ADRM1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ADRM1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ADRM1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ADRM1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, PDAC, and CCRCC are the cancer types where ADRM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.944	0.469	.002	48	view →
PDAC	DFS	Quartile	II,III,IV	0.721	0.904	.001	34	view →
CCRCC	OS	Tertile	All	0.704	0.966	.001	22	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.777	.014	9	view →
LUAD	OS	Median	All	0.634	0.868	.002	8	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ADRM1–UCEC (DFS)

Open the UCEC breakdown →