Across TCGA patient cohorts, ADRB3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. READ shows the largest number of these associations.

The most reproducible ADRB3-associated genes across cancer lineages are Adipocytes, CD4+ memory T-cells, and Epithelial cells. Each is linked with ADRB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRB3-to-partner and partner-to-ADRB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRB3→partner) and Y-score (partner→ADRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Adipocytes →	+0.035	+2.016	.002	.027	3	2
READ	CD4+ memory T-cells →	+0.020	+3.242	<.001	.045	3	2
UCEC	Epithelial cells →	-0.158	-3.159	<.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

ADRB3 survival (RNA) · tumor vs normal (RNA) · all ADRB3 data types