Across TCGA cell cohorts, ADRB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,284 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADRB3-associated GO terms across cancer lineages are Positive regulation of sodium ion transport, Negative regulation of transcription initiation by RNA polymerase II, and Regulation of heterochromatin formation. Each is linked with ADRB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADRB3-to-partner and partner-to-ADRB3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRB3→partner) and Y-score (partner→ADRB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of sodium ion transport →	-0.174	-2.292	<.001	<.001	3	3
BREAST	Negative regulation of transcription initiation by RNA polymerase II →	+0.083	+0.010	.003	.007	3	3
BONE	Regulation of heterochromatin formation →	+0.107	+3.010	<.001	<.001	3	3
BONE	Nucleobase catabolic process →	-1.065	-2.471	<.001	.001	3	3
BREAST	Negative regulation of DNA-templated transcription initiation →	+0.083	+0.010	.003	.007	3	3
BONE	Positive regulation of protein localization to endoplasmic reticulum →	+0.090	+3.074	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,284 associations by consensus.

Exploration

ADRB3 survival (RNA) · tumor vs normal (RNA) · all ADRB3 data types