ADRB2

Across TCGA cell cohorts, ADRB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,818 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADRB2-associated GO terms across cancer lineages are Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure, Response to psychosocial stress, and Positive regulation of plasma membrane repair. Each is linked with ADRB2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ADRB2-to-partner and partner-to-ADRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure grouped by ADRB2-low versus ADRB2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRB2→partner) and Y-score (partner→ADRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure →	+1.814	+2.806	<.001	<.001	3	18
BLOOD_Myeloma	Response to psychosocial stress →	+1.760	+3.046	<.001	<.001	3	16
BONE	Positive regulation of plasma membrane repair →	+0.269	+1.164	<.001	<.001	3	14
LIVER	Positive regulation of chemotaxis →	+0.126	+1.785	.002	<.001	3	14
LIVER	Urokinase plasminogen activator signaling pathway →	+1.229	+1.653	<.001	<.001	3	13
URINARY_TRACT	Adenylate cyclase-inhibiting adrenergic receptor signaling pathway →	+1.690	+2.283	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,818 associations by consensus.

Norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure by ADRB2 expression — URINARY_TRACT

Explore this box plot interactively →