ADRB2

Across TCGA cell cohorts, ADRB2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADRB2-associated genes across cancer lineages are HBG1 and SPANXN2. Each is linked with ADRB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRB2-to-partner and partner-to-ADRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HBG1 grouped by ADRB2-low versus ADRB2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRB2→partner) and Y-score (partner→ADRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HBG1 →	+0.108	+4.054	<.001	.004	3	1
LARGE_INTESTINE	SPANXN2 →	+0.029	+4.217	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

HBG1 by ADRB2 expression — LARGE_INTESTINE

Explore this box plot interactively →