ADRA2B

Across TCGA patient cohorts, ADRA2B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,475 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADRA2B-associated proteins across cancer lineages are BRMS1L, GBF1, and MTA1_S576. Each is linked with ADRA2B in more than 4 cancer types. Because this analysis shows association rather than direction, both ADRA2B-to-partner and partner-to-ADRA2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADRA2B versus BRMS1L in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA2B→partner) and Y-score (partner→ADRA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BRMS1L →	+0.264	+0.530	<.001	.001	3	5
UCEC	GBF1 →	-0.190	-0.612	<.001	.005	3	5
LSCC	MTA1_S576 →	+0.778	+0.851	<.001	<.001	3	4
CCRCC	NRF1 →	+0.258	+1.001	<.001	<.001	3	4
HNSC	PHGDH →	+0.666	+0.972	<.001	.001	3	4
OV	ZNF462_S2172 →	+0.861	+0.739	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,475 associations by consensus.

ADRA2B vs BRMS1L — UCEC

Explore this scatter interactively →