ADRA2B

Across TCGA patient cohorts, ADRA2B protein abundance is significantly associated with the RNA expression of many other genes, with 876 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADRA2B-associated genes across cancer lineages are DMC1, SUN2, and SAMD15. Each is linked with ADRA2B in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRA2B-to-partner and partner-to-ADRA2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADRA2B versus DMC1 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA2B→partner) and Y-score (partner→ADRA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DMC1 →	+1.229	+1.854	.004	.003	3	1
LSCC	SUN2 →	-0.519	-1.463	.001	.002	3	1
LSCC	SAMD15 →	+1.301	+1.797	<.001	.004	3	1
LSCC	IFT52 →	+1.071	+1.688	.001	.008	3	1
LSCC	RIMS4 →	+2.520	+1.638	.001	.008	3	1
LSCC	PFDN4 →	+1.022	+1.832	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 876 associations by consensus.

ADRA2B vs DMC1 — LSCC

Explore this scatter interactively →