ADRA2A

Across TCGA patient cohorts, ADRA2A protein abundance is significantly associated with the RNA expression of many other genes, with 2,134 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ADRA2A-associated genes across cancer lineages are SLC19A3, RAB5CP1, and FGF10-AS1. Each is linked with ADRA2A in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRA2A-to-partner and partner-to-ADRA2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADRA2A versus SLC19A3 in PDAC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA2A→partner) and Y-score (partner→ADRA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC19A3 →	+1.177	+1.003	.003	<.001	3	2
LUAD	RAB5CP1 →	-1.111	-0.760	<.001	.001	3	2
HNSC	FGF10-AS1 →	+0.652	+1.348	.008	.002	3	2
UCEC	RNU6-125P →	-1.604	-0.711	.009	.002	3	2
UCEC	FAM86DP →	-1.135	-0.776	.006	.009	3	2
UCEC	MIR4477B →	-1.556	-0.734	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,134 associations by consensus.

ADRA2A vs SLC19A3 — PDAC

Explore this scatter interactively →