ADRA1D

Across TCGA cell cohorts, ADRA1D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,703 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADRA1D-associated GO terms across cancer lineages are Negative regulation of activation of membrane attack complex, Regulation of cell-substrate junction organization, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with ADRA1D in more than 9 cancer types. Because this analysis shows association rather than direction, both ADRA1D-to-partner and partner-to-ADRA1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of activation of membrane attack complex grouped by ADRA1D-low versus ADRA1D-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA1D→partner) and Y-score (partner→ADRA1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of activation of membrane attack complex →	+0.382	+0.041	.008	.002	2	10
BREAST	Regulation of cell-substrate junction organization →	+0.088	+0.203	<.001	.005	3	7
SKIN	Regulation of ubiquitin-dependent protein catabolic process →	+0.023	+0.346	.003	.006	3	7
LUNG_NSCLC_LUAD	Negative regulation of complement-dependent cytotoxicity →	+0.151	+0.464	<.001	.003	3	7
BREAST	Regulation of focal adhesion assembly →	+0.089	+0.237	<.001	.006	3	7
BREAST	Regulation of cell-substrate junction assembly →	+0.089	+0.237	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,703 associations by consensus.

Negative regulation of activation of membrane attack complex by ADRA1D expression — BLOOD_Lymphoma

Explore this box plot interactively →