ADRA1D

Across TCGA cell cohorts, ADRA1D mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ADRA1D-associated genes across cancer lineages are XAGE5, TSGA13, and GAGE12H. Each is linked with ADRA1D in more than 1 cancer types. Because this analysis shows association rather than direction, both ADRA1D-to-partner and partner-to-ADRA1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE5 grouped by ADRA1D-low versus ADRA1D-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADRA1D→partner) and Y-score (partner→ADRA1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	XAGE5 →	+0.060	+4.247	<.001	<.001	3	1
STOMACH	TSGA13 →	+0.014	+3.632	.002	.009	3	1
STOMACH	GAGE12H →	+0.083	+3.432	<.001	.008	3	1
STOMACH	GAGE12F →	+1.887	+4.280	<.001	.001	3	1
SKIN	KRTAP2-1 →	+0.258	+5.415	<.001	.004	3	1
BREAST	TMEM252 →	+0.185	+3.758	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

XAGE5 by ADRA1D expression — STOMACH

Explore this box plot interactively →