ADPRS

Across TCGA pan-cancer cohorts, ADPRS Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ADPRS data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ADPRS Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ADPRS expression acts as an unfavorable survival marker.

BRCA and UCS are the cancer types where ADPRS Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.211	0.924	<.001	36	view →
UCS	OS	Median	All	0.135	0.687	.009	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ADPRS–BRCA (OS)

Open the BRCA breakdown →