ADPRM

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ADPRM Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ADPRM data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher ADPRM Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ADPRM expression acts as an unfavorable survival marker.

READ and ACC are the cancer types where ADPRM Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
READOSMedianAll0.1730.828<.00139view →
ACCDFSMedianAll0.0480.667<.00118view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ADPRM–READ (OS)

Kaplan–Meier survival curve for ADPRM mutant vs wild-type samples in READ.

Open the READ breakdown →

Exploration