ADPRHL1

Across TCGA cell cohorts, ADPRHL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADPRHL1-associated genes across cancer lineages are ZSCAN1, OR10Q1, and RTL4. Each is linked with ADPRHL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADPRHL1-to-partner and partner-to-ADPRHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZSCAN1 grouped by ADPRHL1-low versus ADPRHL1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRHL1→partner) and Y-score (partner→ADPRHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZSCAN1 →	+0.778	+3.855	<.001	.007	3	1
BLOOD_Leukemia	OR10Q1 →	+0.019	+4.384	<.001	.006	3	1
BLOOD_Leukemia	RTL4 →	+0.023	+4.567	<.001	.001	3	1
BLOOD_Leukemia	GALP →	+0.049	+4.786	<.001	<.001	3	1
BLOOD_Leukemia	NOX3 →	+0.192	+3.769	<.001	.008	3	1
BLOOD_Leukemia	LRP1B →	+0.428	+3.819	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ZSCAN1 by ADPRHL1 expression — BLOOD_Leukemia

Explore this box plot interactively →