ADPRHL1

Across TCGA cell cohorts, ADPRHL1 mutation is significantly associated with the mutation status of many other genes, with 820 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADPRHL1-associated genes across cancer lineages are SLC5A11, ZNF526, and SLC26A2. Each is linked with ADPRHL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADPRHL1-to-partner and partner-to-ADPRHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A11 grouped by ADPRHL1-low versus ADPRHL1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPRHL1→partner) and Y-score (partner→ADPRHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SLC5A11 →	+3.638	+4.117	.002	.002	1	3
SKIN	ZNF526 →	+5.053	+4.239	.007	.007	1	3
SKIN	SLC26A2 →	+5.053	+4.239	.007	.007	1	2
SKIN	TRIM42 →	+2.883	+4.528	.001	.001	1	2
SKIN	NPTN →	+5.053	+4.239	.007	.007	1	2
SKIN	MORC3 →	+5.638	+4.977	<.001	<.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 820 associations by consensus.

SLC5A11 by ADPRHL1 expression — SKIN

Explore this box plot interactively →