ADPGK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ADPGK protein abundance is significantly associated with the RNA expression of many other genes, with 16,386 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADPGK-associated genes across cancer lineages are IL2RA, FCER1G, and PDCD1LG2. Each is linked with ADPGK in more than 6 cancer types. Because this analysis shows association rather than direction, both ADPGK-to-partner and partner-to-ADPGK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADPGK versus IL2RA in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPGK→partner) and Y-score (partner→ADPGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMIL2RA →+1.183+0.351<.001<.00137
OVFCER1G →+0.992+0.221<.001<.00137
OVPDCD1LG2 →+1.091+0.230.001.00337
LUADLILRB1 →+0.908+0.257<.001<.00136
GBMCD86 →+1.130+0.419<.001<.00136
GBMNCKAP1L →+1.166+0.414<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,386 associations by consensus.

ADPGK vs IL2RA — GBM

Per-sample scatter of ADPGK vs IL2RA in GBM (Pearson r = 0.56).

Explore this scatter interactively →

Exploration