ADPGK

Across TCGA patient cohorts, ADPGK mutation is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADPGK-associated genes across cancer lineages are RNU6-947P, SNORD113-1, and MIR328. Each is linked with ADPGK in more than 1 cancer types. Because this analysis shows association rather than direction, both ADPGK-to-partner and partner-to-ADPGK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-947P grouped by ADPGK-low versus ADPGK-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADPGK→partner) and Y-score (partner→ADPGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-947P →	+0.258	+7.816	<.001	.008	3	2
CESC	SNORD113-1 →	+0.329	+5.837	<.001	.001	3	2
BRCA	MIR328 →	+0.463	+5.646	<.001	.004	3	2
UCEC	RNA5SP405 →	+0.234	+2.845	<.001	.009	3	2
COAD	MIR629 →	+0.277	+4.807	.005	.004	3	2
UCEC	RN7SL354P →	+0.241	+1.736	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

RNU6-947P by ADPGK expression — SKCM

Explore this box plot interactively →