ADORA2BP1

Across TCGA pan-cancer cohorts, ADORA2BP1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ADORA2BP1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ADORA2BP1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADORA2BP1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and ESCA show a favorable association.

SKCM, ESCA, and UCEC are the cancer types where ADORA2BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	IV	0.828	0.309	.003	56	view →
ESCA	DFS	Quartile	III,IV	0.572	0.272	.002	34	view →
UCEC	DFS	Tertile	All	0.842	0.922	<.001	32	view →
LIHC	OS	Median	II,III,IV	0.804	0.579	.002	28	view →
KICH	DFS	Tertile	All	0.705	1.000	.011	25	view →
LGG	OS	Median	All	0.365	0.505	.004	21	view →
THYM	DFS	Tertile	III,IV	0.445	1.000	.004	15	view →
KIRC	OS	Quartile	All	0.734	0.828	.016	11	view →
THCA	DFS	Quartile	III,IV	0.697	0.912	.003	10	view →
MESO	DFS	Tertile	III,IV	0.515	0.321	.031	9	view →
ACC	OS	Quartile	All	0.659	0.814	.010	8	view →
READ	DFS	Tertile	IV	0.221	0.936	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ADORA2BP1–SKCM (OS)

Open the SKCM breakdown →