ADORA2B

Across TCGA patient cohorts, ADORA2B mutation is significantly associated with the RNA expression of many other genes, with 620 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADORA2B-associated genes across cancer lineages are LINC01707, MIR6133, and NOCT. Each is linked with ADORA2B in more than 1 cancer types. Because this analysis shows association rather than direction, both ADORA2B-to-partner and partner-to-ADORA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01707 grouped by ADORA2B-low versus ADORA2B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADORA2B→partner) and Y-score (partner→ADORA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01707 →	+0.147	+5.693	.008	.003	3	2
SKCM	MIR6133 →	+0.291	+4.867	<.001	.005	3	1
UCEC	NOCT →	+1.055	+3.332	<.001	.005	3	1
UCEC	GUF1 →	+0.622	+3.332	.001	.005	3	1
UCEC	VPS37A →	+0.766	+3.332	.001	.005	3	1
UCEC	SUPV3L1 →	+0.478	+3.332	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 620 associations by consensus.

LINC01707 by ADORA2B expression — COAD

Explore this box plot interactively →