ADORA2B

Across TCGA cell cohorts, ADORA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,282 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ADORA2B-associated GO terms across cancer lineages are Regulation of cell-matrix adhesion, Cytosolic ciliogenesis, and Regulation of protein processing. Each is linked with ADORA2B in more than 9 cancer types. Because this analysis shows association rather than direction, both ADORA2B-to-partner and partner-to-ADORA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-matrix adhesion grouped by ADORA2B-low versus ADORA2B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADORA2B→partner) and Y-score (partner→ADORA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-matrix adhesion →	+0.116	+1.978	<.001	<.001	3	10
BREAST	Cytosolic ciliogenesis →	+0.114	+1.641	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of protein processing →	+0.217	+2.417	.001	.003	3	10
LUNG_NSCLC_LUSC	Regulation of protein maturation →	+0.198	+2.299	.003	.004	3	10
BONE	Regulation of monocyte aggregation →	+1.320	+1.952	<.001	<.001	3	10
BONE	Positive regulation of monocyte aggregation →	+1.320	+1.952	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,282 associations by consensus.

Regulation of cell-matrix adhesion by ADORA2B expression — BONE

Explore this box plot interactively →