ADORA1

Across TCGA patient cohorts, ADORA1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,928 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADORA1-associated genes across cancer lineages are SEC14L2, PRODH, and SLC25A1. Each is linked with ADORA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADORA1-to-partner and partner-to-ADORA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADORA1 versus SEC14L2 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADORA1→partner) and Y-score (partner→ADORA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC14L2 →	+0.495	+0.465	.001	.003	3	1
GBM	PRODH →	+0.865	+0.482	<.001	.002	3	1
GBM	SLC25A1 →	-0.367	-0.461	.001	.008	3	1
GBM	JOSD1 →	-0.296	-0.576	.007	.004	3	1
GBM	MCM5 →	-0.521	-0.691	.004	<.001	3	1
GBM	SYNGR1 →	+0.901	+0.552	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,928 associations by consensus.

ADORA1 vs SEC14L2 — GBM

Explore this scatter interactively →