ADORA1

Across TCGA cell cohorts, ADORA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ADORA1-associated GO terms across cancer lineages are Negative regulation of glutamate secretion, Negative regulation of circadian sleep/wake cycle, sleep, and Positive regulation of nucleobase-containing compound transport. Each is linked with ADORA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both ADORA1-to-partner and partner-to-ADORA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of glutamate secretion grouped by ADORA1-low versus ADORA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADORA1→partner) and Y-score (partner→ADORA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of glutamate secretion →	+1.918	+2.834	<.001	<.001	3	17
LIVER	Negative regulation of circadian sleep/wake cycle, sleep →	+1.889	+3.719	.001	<.001	3	16
BONE	Positive regulation of nucleobase-containing compound transport →	-0.170	-2.390	<.001	<.001	3	14
LUNG_SCLC	Regulation of circadian sleep/wake cycle, non-REM sleep →	-0.290	-1.774	<.001	<.001	3	14
STOMACH	Regulation of respiratory gaseous exchange by nervous system process →	+1.429	+2.182	<.001	.001	3	13
LIVER	Regulation of neurotrophin production →	+1.615	+3.264	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Negative regulation of glutamate secretion by ADORA1 expression — OVARY

Explore this box plot interactively →