ADO

Across TCGA patient cohorts, ADO RNA expression is significantly associated with the protein abundance of many other proteins, with 16,246 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ADO-associated proteins across cancer lineages are PARG, KIFBP, and DBN1. Each is linked with ADO in more than 4 cancer types. Because this analysis shows association rather than direction, both ADO-to-partner and partner-to-ADO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADO versus PARG in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADO→partner) and Y-score (partner→ADO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PARG →	+0.275	+0.588	<.001	<.001	3	5
GBM	KIFBP →	+0.271	+0.291	<.001	<.001	3	5
LUAD	DBN1 →	+0.409	+0.326	<.001	<.001	3	5
LUAD	PPFIBP2_S329 →	-0.828	-0.315	.001	.002	3	4
GBM	P4HB →	-0.371	-0.363	<.001	<.001	3	4
GBM	SCAPER →	+0.228	+0.365	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,246 associations by consensus.

ADO vs PARG — LSCC

Explore this scatter interactively →