ADNP2

Across TCGA patient cohorts, ADNP2 mutation is significantly associated with the RNA expression of many other genes, with 2,773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADNP2-associated genes across cancer lineages are MIR4774, RPL7P35, and SPATA48. Each is linked with ADNP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ADNP2-to-partner and partner-to-ADNP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4774 grouped by ADNP2-low versus ADNP2-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADNP2→partner) and Y-score (partner→ADNP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MIR4774 →	+0.627	+5.257	<.001	.002	3	3
UCEC	RPL7P35 →	+0.068	+1.633	<.001	.004	3	3
LIHC	SPATA48 →	+0.023	+4.647	<.001	.007	3	2
COAD	SS18L2P1 →	+0.754	+3.373	<.001	.004	3	2
LIHC	RN7SL447P →	+0.147	+5.305	<.001	.003	3	2
SKCM	SNRPGP12 →	+0.064	+2.913	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,773 associations by consensus.

MIR4774 by ADNP2 expression — READ

Explore this box plot interactively →