ADNP2

Across TCGA cell cohorts, ADNP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,007 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADNP2-associated GO terms across cancer lineages are Heterochromatin organization, Constitutive heterochromatin formation, and Epigenetic regulation of gene expression. Each is linked with ADNP2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ADNP2-to-partner and partner-to-ADNP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by ADNP2-low versus ADNP2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADNP2→partner) and Y-score (partner→ADNP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Heterochromatin organization →	+0.067	+0.925	<.001	<.001	3	16
SOFT_TISSUE	Constitutive heterochromatin formation →	+0.089	+0.772	<.001	<.001	3	15
OVARY	Epigenetic regulation of gene expression →	+0.066	+0.684	<.001	<.001	3	15
BONE	Positive regulation of DNA replication →	+0.128	+0.904	.001	<.001	3	15
BONE	Host-mediated activation of viral transcription →	+0.105	+0.671	<.001	<.001	3	15
BONE	Regulation of chromatin organization →	+0.078	+0.496	.001	.007	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,007 associations by consensus.

Heterochromatin organization by ADNP2 expression — LARGE_INTESTINE

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