ADNP2

Across TCGA cell cohorts, ADNP2 mutation is significantly associated with the RNA expression of many other genes, with 289 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADNP2-associated genes across cancer lineages are CRYGD, BPIFA1, and ZNF728. Each is linked with ADNP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADNP2-to-partner and partner-to-ADNP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGD grouped by ADNP2-low versus ADNP2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADNP2→partner) and Y-score (partner→ADNP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CRYGD →	+0.418	+4.415	<.001	.007	3	2
KIDNEY	BPIFA1 →	+0.036	+5.000	<.001	.005	3	1
KIDNEY	ZNF728 →	+0.013	+5.000	<.001	.005	3	1
LUNG_SCLC	PZP →	+0.061	+4.044	<.001	.009	3	1
LUNG_SCLC	CCDC197 →	+0.044	+4.269	.008	.005	3	1
LUNG_SCLC	OR5B21 →	+0.055	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 289 associations by consensus.

CRYGD by ADNP2 expression — SKIN

Explore this box plot interactively →