ADNP2

Across TCGA cell cohorts, ADNP2 mutation is significantly associated with the mutation status of many other genes, with 4,658 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADNP2-associated genes across cancer lineages are COL4A5, DHX37, and CARD14. Each is linked with ADNP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADNP2-to-partner and partner-to-ADNP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL4A5 grouped by ADNP2-low versus ADNP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADNP2→partner) and Y-score (partner→ADNP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	COL4A5 →	+2.823	+3.665	.008	.008	1	5
BREAST	DHX37 →	+5.297	+5.297	.004	.004	1	4
OVARY	CARD14 →	+4.415	+4.977	.007	.007	1	4
OVARY	MINAR1 →	+4.415	+4.977	.007	.007	1	4
BLOOD_Leukemia	SLC12A1 →	+3.560	+4.247	.002	.002	1	4
STOMACH	RPL22 →	+3.440	+3.115	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,658 associations by consensus.

COL4A5 by ADNP2 expression — BLOOD_Leukemia

Explore this box plot interactively →