ADNP-AS1

Across TCGA pan-cancer cohorts, ADNP-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ADNP-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ADNP-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ADNP-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

UCS, SKCM, and LGG are the cancer types where ADNP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.618	0.203	<.001	78	view →
SKCM	DFS	Tertile	All	0.267	0.121	<.001	49	view →
LGG	DFS	Median	All	0.782	0.877	<.001	37	view →
UCEC	DFS	Tertile	All	0.506	0.751	.001	36	view →
COAD	DFS	Median	All	0.577	0.792	<.001	32	view →
LIHC	OS	Tertile	II,III,IV	0.365	0.546	.020	19	view →
BRCA	DFS	Tertile	III,IV	0.858	0.717	.011	15	view →
STAD	OS	Tertile	III,IV	0.728	0.431	.004	15	view →
UVM	DFS	Median	III,IV	0.220	0.664	.020	12	view →
BLCA	OS	Median	II,III,IV	0.781	0.649	.004	12	view →
LUSC	DFS	Quartile	III,IV	0.476	0.762	.005	11	view →
KICH	DFS	Median	III,IV	0.299	1.000	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ADNP-AS1–UCS (OS)

Open the UCS breakdown →