ADM2

Across TCGA patient cohorts, ADM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,609 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ADM2-associated proteins across cancer lineages are SHMT2, CCDC134, and ZER1. Each is linked with ADM2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADM2-to-partner and partner-to-ADM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ADM2 versus SHMT2 in CCRCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADM2→partner) and Y-score (partner→ADM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SHMT2 →	+0.574	+0.825	<.001	<.001	3	5
HNSC	CCDC134 →	+0.437	+0.913	<.001	<.001	3	5
OV	ZER1 →	-0.232	-0.644	.008	.005	3	4
BRCA	ASNS →	+0.652	+0.943	<.001	<.001	3	4
HNSC	HYOU1 →	+0.279	+0.842	<.001	<.001	3	4
UCEC	MTHFD2 →	+0.504	+0.814	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,609 associations by consensus.

ADM2 vs SHMT2 — CCRCC

Explore this scatter interactively →