ADM2

Across TCGA patient cohorts, ADM2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ADM2-associated genes across cancer lineages are LINC02164, DSC1, and RN7SKP290. Each is linked with ADM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADM2-to-partner and partner-to-ADM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02164 grouped by ADM2-low versus ADM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADM2→partner) and Y-score (partner→ADM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02164 →	+0.296	+6.027	<.001	.002	3	2
SCLC	DSC1 →	+0.102	+4.847	.002	.009	3	1
UCEC	RN7SKP290 →	+0.631	+5.358	<.001	.006	3	1
UCEC	MIR6839 →	+0.926	+5.299	<.001	.006	3	1
BRCA	OR11H3P →	+0.069	+9.057	<.001	.003	3	1
BRCA	MIR129-1 →	+0.453	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

LINC02164 by ADM2 expression — UCEC

Explore this box plot interactively →