ADM2

Across TCGA cell cohorts, ADM2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADM2-associated genes across cancer lineages are C6orf118, DEFA4, and GSG1L2. Each is linked with ADM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADM2-to-partner and partner-to-ADM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by ADM2-low versus ADM2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADM2→partner) and Y-score (partner→ADM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.208	+3.793	<.001	.007	3	1
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

C6orf118 by ADM2 expression — LARGE_INTESTINE

Explore this box plot interactively →