ADIPOR2

Across TCGA cell cohorts, ADIPOR2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADIPOR2-associated genes across cancer lineages are TGM7, KRTAP4-5, and SPATA31D1. Each is linked with ADIPOR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ADIPOR2-to-partner and partner-to-ADIPOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM7 grouped by ADIPOR2-low versus ADIPOR2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIPOR2→partner) and Y-score (partner→ADIPOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRTAP4-5 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	SPATA31D1 →	+0.006	+5.228	<.001	.005	3	1
BLOOD_Leukemia	OPRM1 →	+0.025	+5.201	<.001	.006	3	1
BLOOD_Leukemia	KCNA4 →	+0.028	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR4F15 →	+0.006	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

TGM7 by ADIPOR2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →