ADIPOQ

Across TCGA patient cohorts, ADIPOQ RNA expression is significantly associated with the go_rna of many other GO terms, with 6,687 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ADIPOQ-associated GO terms across cancer lineages are Regulation of actin filament organization, Regulation of actomyosin structure organization, and Negative regulation of supramolecular fiber organization. Each is linked with ADIPOQ in more than 14 cancer types. Because this analysis shows association rather than direction, both ADIPOQ-to-partner and partner-to-ADIPOQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by ADIPOQ-low versus ADIPOQ-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIPOQ→partner) and Y-score (partner→ADIPOQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of actin filament organization →	+0.065	+0.344	<.001	<.001	3	15
ESCA	Regulation of actomyosin structure organization →	+0.078	+0.105	<.001	.002	3	14
ESCA	Negative regulation of supramolecular fiber organization →	+0.073	+0.119	<.001	<.001	2	15
STAD	Actin polymerization or depolymerization →	+0.086	+0.473	<.001	<.001	3	14
STAD	Positive regulation of endothelial cell proliferation →	+0.053	+0.469	<.001	<.001	3	14
STAD	Regulation of actin filament length →	+0.067	+0.452	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,687 associations by consensus.

Regulation of actin filament organization by ADIPOQ expression — STAD

Explore this box plot interactively →