ADIPOQ

Across TCGA cell cohorts, ADIPOQ RNA expression is significantly associated with the mutation status of many other genes, with 112 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ADIPOQ-associated genes across cancer lineages are PTPRS, KDM6B, and FOXC1. Each is linked with ADIPOQ in more than 2 cancer types. Because this analysis shows association rather than direction, both ADIPOQ-to-partner and partner-to-ADIPOQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTPRS grouped by ADIPOQ-low versus ADIPOQ-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ADIPOQ→partner) and Y-score (partner→ADIPOQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PTPRS →	+3.472	+0.006	.002	<.001	3	3
SKIN	KDM6B →	+3.217	+0.003	.006	<.001	3	2
LUNG_NSCLC_LUAD	FOXC1 →	+4.813	+0.019	<.001	<.001	3	2
LARGE_INTESTINE	MIB2 →	+2.172	+0.005	.007	<.001	3	2
BLOOD_Leukemia	ABCB4 →	+3.269	+0.016	.007	<.001	3	2
SKIN	EXD3 →	+3.632	+0.004	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 112 associations by consensus.

PTPRS by ADIPOQ expression — BLOOD_Lymphoma

Explore this box plot interactively →