Across TCGA pan-cancer cohorts, ADIPOQ-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated ADIPOQ-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ADIPOQ-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ADIPOQ-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML and KIRC show a favorable association.

KICH, CHOL, and ESCA are the cancer types where ADIPOQ-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	II,III,IV	0.794	0.973	.007	69	view →
CHOL	DFS	Tertile	All	0.103	0.533	.007	54	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
STAD	DFS	Tertile	IV	0.087	0.415	<.001	32	view →
OV	OS	Tertile	All	0.773	0.858	.005	30	view →
BLCA	DFS	Tertile	IV	0.225	0.487	.003	27	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
READ	OS	Tertile	III,IV	0.227	0.795	<.001	18	view →
HNSC	OS	Tertile	All	0.652	0.761	.030	15	view →
UCEC	DFS	Tertile	III,IV	0.694	0.807	.038	12	view →
LAML	DFS	Tertile	All	0.711	0.487	.022	12	view →
KIRC	DFS	Tertile	III,IV	0.660	0.436	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration

Same gene, other analysis: ADIPOQ-AS1 tumor-vs-normal RNA expression · all ADIPOQ-AS1 data types