ADI1

Across TCGA patient cohorts, ADI1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,450 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ADI1-associated proteins across cancer lineages are F11R, SLC25A4, and HOOK2. Each is linked with ADI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ADI1-to-partner and partner-to-ADI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F11R grouped by ADI1-low versus ADI1-high in LSCC.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ADI1→partner) and Y-score (partner→ADI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	F11R →	+0.396	+0.440	<.001	.001	3	5
PDAC	SLC25A4 →	+0.566	+0.317	<.001	.002	3	4
LUAD	HOOK2 →	+0.299	+0.570	<.001	<.001	3	4
HNSC	KRTCAP3 →	+0.475	+0.679	<.001	.008	3	4
HNSC	SPAST →	+0.438	+0.675	<.001	<.001	3	4
LSCC	SPR →	+0.381	+0.478	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,450 associations by consensus.

F11R by ADI1 expression — LSCC

Explore this box plot interactively →