Across TCGA cell cohorts, ADI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,450 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADI1-associated GO terms across cancer lineages are L-methionine metabolic process, Cellular response to ionizing radiation, and Cellular response to cisplatin. Each is linked with ADI1 in more than 10 cancer types. Because this analysis shows association rather than direction, both ADI1-to-partner and partner-to-ADI1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADI1→partner) and Y-score (partner→ADI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	L-methionine metabolic process →	+0.143	+1.212	<.001	<.001	3	11
BREAST	Cellular response to ionizing radiation →	+0.062	+0.634	<.001	.001	3	8
OVARY	Cellular response to cisplatin →	+0.110	+0.619	.001	.006	3	7
UPPER_AERODIGESTIVE_TRACT	DTMP biosynthetic process →	+0.209	+0.968	.008	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Pyrimidine deoxyribonucleoside monophosphate biosynthetic process →	+0.209	+0.968	.008	.005	3	7
BREAST	Negative regulation of mitotic cell cycle phase transition →	+0.063	+0.675	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,450 associations by consensus.

Exploration

ADI1 survival (RNA) · tumor vs normal (RNA) · all ADI1 data types