ADHFE1

Across TCGA cell cohorts, ADHFE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,390 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ADHFE1-associated GO terms across cancer lineages are Macroautophagy, Negative regulation of myoblast fusion, and Ketone body catabolic process. Each is linked with ADHFE1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ADHFE1-to-partner and partner-to-ADHFE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by ADHFE1-low versus ADHFE1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ADHFE1→partner) and Y-score (partner→ADHFE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.067	+1.463	<.001	.001	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.143	+1.493	<.001	<.001	3	13
LUNG_SCLC	Ketone body catabolic process →	-0.214	-0.626	.001	<.001	3	13
OESOPHAGUS	Vacuolar transport →	+0.061	+1.498	<.001	<.001	3	13
OESOPHAGUS	Regulation of myoblast fusion →	+0.126	+1.386	<.001	<.001	3	12
OESOPHAGUS	Protein stabilization →	+0.067	+1.668	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,390 associations by consensus.

Macroautophagy by ADHFE1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →